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AMD and Nutanix Forge $250M Strategic Partnership to Build Open Enterprise AI Infrastructure

Deepa Sharma by Deepa Sharma
February 26, 2026
AMD and Nutanix

Advanced Micro Devices (AMD) and Nutanix have announced a multi-year strategic partnership to jointly develop an open enterprise AI infrastructure platform designed for scalable, production-ready artificial intelligence deployments across data centre, hybrid cloud and edge environments. Under the agreement, AMD will make a strategic investment in Nutanix common stock and provide additional funding to support collaborative engineering and go-to-market efforts for the initiative.

The partnership centres on integrating key AMD technologies, including AMD ROCm software, AMD Enterprise AI tools, EPYC central processing units (CPUs) and Instinct graphics processing units (GPUs), into Nutanix’s cloud and Kubernetes platforms to create an interoperable hardware and software stack for enterprises. The first jointly engineered agentic AI platform is expected to reach the market in late 2026, reflecting the companies’ efforts to position an open, flexible alternative to more tightly coupled AI infrastructure solutions.

Dual Investment and Strategic Focus

As part of the agreement announced on February 25, 2026, AMD plans to invest $150 million in Nutanix shares at a set price per share, alongside up to $100 million in incremental funding for joint research, engineering development and market engagement. The equity investment is expected to close in the second quarter of 2026.

The strategic partnership links AMD’s silicon and software capabilities with Nutanix’s hybrid cloud and orchestration expertise, with the shared objective of simplifying deployment and lifecycle management for AI workloads.

Building for Agentic AI and Inference Workloads

Industry trends suggest enterprise AI deployments are increasingly prioritising inference, the execution and real-time use of trained AI models, and agentic applications that act on complex task sets autonomously. The open enterprise AI infrastructure platform under development is designed to support these workloads through optimised compute, data orchestration and seamless system management.

Dan McNamara, senior vice president and general manager of Compute and Enterprise AI at AMD, said, “Through our partnership with Nutanix, we’re building a scalable, full-stack AI platform rooted in openness, designed to give enterprises and service providers the flexibility to innovate, extend and grow AI deployments across Enterprises.”

Tarkan Maner, President and Chief Commercial Officer, Nutanix, “Our partnership with AMD reflects a shared vision for scalable, production-ready AI infrastructure. Together, we are delivering full-stack, integrated platforms optimised for inference and agentic applications across hybrid environments for enterprises and service providers.”

Also Read: AMD and Meta Expand Multiyear AI Infrastructure Partnership

Deepa Sharma

Deepa Sharma

Deepa Sharma is CXOVoice’s Managing Editor, overseeing coverage of technology, cybersecurity, banking, and financial services. She can be reached at [email protected].

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